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Sunday, January 27, 2013
What It's Like To Go Off the World's Largest Ski Jump
Saturday, January 26, 2013
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Source: http://www.reviewsilo.com/my-online-internet-business-killer-conversions-review/
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Friday, January 25, 2013
Astrophile: Split personality tarnishes pulsars' rep
Astrophile is our weekly column on curious cosmic objects, from the solar system to the far reaches of the multiverse
Object: Pulsar (pulsing star)
Behaviour: Erratic
A split personality can be disturbing, especially when it affects someone you least expected it to. Now it seems stars, too, can have disturbingly fractured personas. The discovery of the first pulsar that shines at different frequencies at different times is tarnishing the reputation of this class of pulsing dead star. Until now, pulsars have been relied upon as cosmic timekeepers, but perhaps we can't take their regularity for granted any longer.
We had thought of pulsars ? the dense remnants of exploded stars ? as emitting radio waves, X-rays or gamma rays in bursts of such regularity that you could practically set your watch by them. Pulsars are spinning neutron stars, with strong magnetic fields that emit beams of radiation from their poles. The poles are offset from the axis of rotation ? just as the magnetic poles on Earth do not line up with true north and south. This offset means the beams sweep around like a lighthouse as the pulsar rotates, giving the star's radiation a distinctive pulse when viewed from a distance.
Individual pulsars can emit radiation at a range of frequencies, from radio waves to gamma rays, and some radio pulsars have been seen to dim or even stop broadcasting all together. That finding had previously cast some doubt on pulsars' otherwise impeccable reputation for dependability.
The latest discovery takes that to a new level, though. When Wim Hermsen of the Netherlands Institute for Space Research in Utrecht and colleagues took the first simultaneous measurements of both the radio and gamma radiation from B0943+10, a pulsar known to emit at both frequencies, they got a shock.
Radio flip
Rather than shining continuously as the team expected, B0943+10 flips at the drop of a hat, toning down its radio emissions for a few hours while pumping out extra X-rays, before switching back as if nothing had happened ? a totally new type of pulsar behaviour. "This variability has never been seen before," says Hermsen.
The pulsar's first personality is similar to that of its more stable siblings. In this mode, the pulsar emits a beam of radio waves from its pole and rotates every 1.1 seconds, while also emitting low-level background X-rays in every direction.
Every few hours though ? exactly when seems random ? the pulsar switches to its second personality. The main radio beam strength halves, though its timing remains the same, and is accompanied by another, even weaker radio signal just before the main pulse. Meanwhile the X-ray output doubles and pulses in time with the star's spin. Some time later, it switches back.
Astronomers already disagree over whether pulsar emissions are created by annihilation of particles close to the surface or further out but still within the pulsar's magnetic field. B0943+10's quirks throw a further spanner in the works because they don't fit either picture. What could be going on?
Cosmic act
One explanation is that what looks a radio-to-X-ray pulsar personality transplant is actually just an act. The object basically remains a radio pulsar, but whenever the radio beam halves in strength, the pulsar's magnetic field switches on a second radio beam in a different direction, which does not sweep past Earth.
In this scenario, the second radio beam is accompanied by increased X-ray emissions. Since they are produced in all directions, they are visible from Earth. If that's true, it would be rather like ascribing a friend's odd behaviour to a personality problem ? only to discover that there was in fact an explanation for the behaviour that was consistent with the person as you normally think of them.
Even this explanation raises obvious questions, such as why a second radio beam is triggered and how that boosts the pulsar's X-ray emissions. That's a problem, given that pulsars are used to search for the effects of gravitational waves - these ripples in spacetime should change pulsars' apparent frequency - and have even been touted as replacing satellites in a kind of GPS for deep space. "Whatever is creating this beam in one mode stops in the other mode, and for that you need something drastic," says Hermsen. "None of the known models can explain it."
Journal reference: Science, DOI: 10.1126/science.1230960
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Ore. suspect's jihadi magazine writing highlighted
FILE - This file image released Nov. 27, 2010, by the Multnomah County Sheriff's Office shows Mohamed Osman Mohamud. Testimony from an undercover agent who posed as an al-Qaida recruiter continues Tuesday, Jan. 15, 2013, in the trial of Mohamud. A second man, who posed as an al-Qaida bomb expert, is also expected to testify. (AP Photo/Multnomah County Sheriff's Office, file)
FILE - This file image released Nov. 27, 2010, by the Multnomah County Sheriff's Office shows Mohamed Osman Mohamud. Testimony from an undercover agent who posed as an al-Qaida recruiter continues Tuesday, Jan. 15, 2013, in the trial of Mohamud. A second man, who posed as an al-Qaida bomb expert, is also expected to testify. (AP Photo/Multnomah County Sheriff's Office, file)
FILE - A Nov. 27, 2010 file photo provided by the Multnomah County Sheriff's Office shows Mohamed Mohamud. Justice Department attorneys Monday focused on the contact between the Oregon terrorism-sting suspect and suspected terrorists overseas in the opening salvo of their case. FBI agent Miltiadis Trousas said government agents first found Mohamud because of his emails to an American-born al-Qaida recruiter. (AP Photo/Mauthnomah County Sheriff's Office, File)
PORTLAND, Ore. (AP) ? In a slow, dispassionate monotone, an FBI agent on Thursday read selections from an Oregon terrorism suspect's contributions to a jihadi magazine as prosecutors attempted to establish Mohamed Mohamud's mindset in the year before his arrest.
Mohamud's federal terrorism trial is in its third week, and prosecutors have tried to show Mohamud was predisposed to committing terrorism before a monthslong sting operation culminated with his November 2010 arrest.
As a teenager in 2009, Mohamud contributed to the online, English-language jihadi magazine "Jihad Recollections."
His contributions to the publication varied in focus and appeared alongside articles written by Osama bin Laden and other al-Qaida higher-ups.
While bin Laden wrote a piece called "Four practical steps to expand global jihad," Mohamud's contributions were more innocuous and included a workout advice column to jihadis fighting in war zones. That column earned Mohamud the nickname "Osama Gym Laden" from a British tabloid.
In opening statements, one of Mohamud's defense attorneys described the workout advice from Mohamud as being akin to "high school gym class."
On Thursday, Assistant U.S. Attorney Pam Holsinger pointed out a photo above the story, which included masked men holding guns.
"Does this look like high school gym class?" she asked FBI agent Ryan Dwyer.
Dwyer replied, "It does not."
Establishing Mohamud's state of mind before the FBI targeted him in a terrorism sting operation is key to the prosecution's assertion that it did not entrap a then-teenager, as his defense claims.
Mohamud's pseudonymous contributions to "Jihad Recollections" were made public soon after his indictment on charges that he attempted to detonate a bomb at Portland's 2010 Christmas-tree lighting ceremony. The bomb was a fake supplied by undercover FBI agents.
Jurors heard at least one straight hour of content from the magazine, read by Dwyer. The articles, written by a variety of authors other than Mohamud, were aimed at radicalizing Muslims in the U.S. and included advice on bringing recent Muslim converts into a war against the West.
The issue was a significant one at the time Mohamud was writing ? more than a dozen Somali teenagers left Minneapolis in 2009, apparently en route to join a global jihad. The magazine also tracked with terror cases in the U.S., praising both the massacre at Fort Hood, outside Killeen, Texas, and an attempted bombing in Times Square.
Mohamud's defense team showed dozens of text messages intercepted by the FBI during his first year at Oregon State University. They showed a teenager preoccupied with partying, drinking and using marijuana.
By his sophomore year, after he'd began working with undercover FBI agents to plot an attack, Mohamud began telling friends that he was trying to give up drinking and partying. But the messages were interspersed with others asking for marijuana or talking about a night of partying.
Interactions with Mohamud's parents indicated they were having marital problems. In September, Mohamud's father texted, "Also, I need ur help. I'm thinking of bringing back your mom..."
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Tuesday, January 22, 2013
DTI revives bid to relax foreign restrictions in construction industry ...
InterAksyon.com
The online news portal of TV5
MANILA - Construction industry players are bucking the government?s move to allow 100-percent foreign-led contractors in private projects.
According to a notice?on the Department of Trade and Industry (DTI) website, the Philippine Contractors Accreditation Board (PCAB) will hold public consultations on the proposed amendments to the implementing rules and regulations of Republic Act No. 4566 or the Contractors? License Law,?particularly on the 60-percent Filipino, 40-percent foreign equity requirement.
PCAB is the body that issues licenses to contractors. Under RA 4566, all contractors - including subcontractors and specialty contractors - must secure a license from PCAB.
Construction industry sources told InterAksyon.com that the DTI wants to lift the 60-40 equity rule so fully foreign-owned contractors may secure a regular PCAB license and do business in the private construction market.
Sources said the DTI believes that such a move would increase?foreign direct investment (FDI) in the construction industry as well as facilitate a faster rollout of the public-private partnership (PPP) program.
The DTI has been pushing for a relaxation of foreign ownership restrictions in construction as early as two years ago.?DTI officials sought by InterAksyon.com would not comment.
For local construction companies, however, increasing the participation of foreigners in the sector would not necessarily result in more FDI.
"Existing laws already allow the participation of 100-percent foreign-owned construction contractors in BOT [build-operate-transfer] as well as PPP projects. Yet, they have not come in," Philippine Constructors Association Inc executive director Manolito P. Madrasto told InterAksyon.com.
"Construction contractors are service providers and are not known to be involved as direct investors on the structures they build. Contractors are not developers. Lifting the 60-40 equity rule will not translate to an increase in foreign direct investments," he said.
Local construction firms fear that the government proposal "merely wants to give foreign contractors a new market to work in as the global financial crisis has slowed down if not closed"?construction markets in Asean, China, Europe, Japan, South Korea and the US, Madrasto said.
Such a move is unfortunate at a time when the Philippine economy is doing well and private construction is booming, hence more projects for local contractors, he said.?"The entry of hungry foreign contractors will crowd out the locals out of their own market."
"The government wants the local industry to go overseas but is pushing for changes in existing laws that would deter locals from competing overseas. How? To compete, one has to have experience of specific type and size of projects. But if the government wants the foreigners to have control of such types and sizes of projects, then locals can never qualify," he said.
Safety may also be compromised if 100-percent foreign contractors will be allowed to operate in the country, Madrasto said.
"Under the civil code, the contractor is responsible for the structural aspect of its project for 15 years. If the contractor is 100-percent foreign-owned, makakasiguro ka bang nandito pa "yan kapag nagkaproblema? Sino ang hahabulin ng gobyerno?" he said.
Madrasto said the PCA may be amenable to the government proposal to allow fully foreign-owned contractors to operate here if they are to comply with the following conditions:
- 100-percent foreign contractors have P1-billion paid-up capital;
- They can only participate in projects each worth P10-billion and above; and
- The authorized managing officer is a Filipino citizen.
"The small local contractors should be protected," Madrasto said.
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Monday, January 21, 2013
RSS Feed Search Engine - Real-Time Search Powered by FeedRank
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Source: http://www.rssmicro.com/rss.web?q=President
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Web design, Cheap web design, affordable web design blog ...
How to generate Traffic for a Blog Site
Monday, January 21, 2013??? 5:39 amFor you generate traffic for your blog site, it is imperative that you make use of some tactics for internet marketing.? This is what this article would help you understand.? There are so many aspects of traffic generation packages that this article would help you with. This is the reason why we are bringing this online business article to help you get the best.
The Video Marketing-It is now simple to create video that would be used for marketing. This is what would help a blog site stand out effectively and better.? Each day, a lot of people are seen making use of these videos for their marketing of their blog sites with traffic generation.? Because of the number of people who are always online, watching videos have become a great means of making online business traffic increase.? There are lots of in videos that would give a user an idea of what to do with marketing video. YouTube and Daily Motion is what would help a user market his or her goods with videos. This is what can help blog site owners in getting the most exclusive in video marketing traffic generation.
There is another reason why you would always go for video for online business marketing; it is a great way of making relationship and also giving a personal approach to marketing. Social life has been improved with video marketing for those who would want to interact freely with their consumers. And there is an increase in online business demand. Just like the stick ability of articles so is video marketing. You can easily make your video and then leave them for years on some video directories.Online business would not go far without traffic generation. This is what a lot of businesses online are making use of for their traffic generation.
Article marketing package ? A lot of people are today making use of article marketing because of the effectiveness of the generating traffic. These articles are submitted to different directories that are online. This is what would help in making business blog and personal including eCommerce blog site stand out with traffic generation. And with the way the package is popular, a lot of blog sites are making sure that they write articles for their improvement of online business SERP ranking.? When you are able to make use of this online business article for marketing of articles, you have one way of taking of traffic generation.
Source: http://www.bestwebsitesdesigner.com/web-design/how-to-generate-traffic-for-a-blog-site/
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Snow cancels flights in UK, France
By Rhys Jones, Reuters
LONDON -- London's Heathrow Airport canceled a fifth of flights and airlines scrapped 40 percent of flights to Paris' main airports as snow continued to blanket parts of Europe, with more forecast.?
Heathrow Ltd, which is owned by Spain's Ferrovial, said the reduced schedule -- amounting to about 250 fewer flights -- would help it cope with the expected snowfall without making further cancellations.?
"There is a high probability of around two to six centimeters of accumulating snow and low visibility at periods throughout the day," a Heathrow spokesman said.?
"This will reduce the capacity of the airport and without action would cause significant disruption to passengers and flights."
The Paris airport operator, ADP, said airlines scrapped 40 percent of flights into and out of the two main airports on the outskirts of Paris, Charles de Gaulle and Orly, primarily reducing short-haul services.?
London's smaller Stansted and Gatwick airports said they were operating as normal on Sunday morning but that delays and some flight cancellations were likely.?
Weather forecaster the Met Office said snow was likely to continue throughout Sunday and into Monday. As much as eight centimeters was expected in southeast England on Sunday, it said.
On average, some 1,300 flights leave Heathrow daily. The airport, Europe's busiest, operates at close to full capacity after Britain's coalition government blocked development of a third runway in 2010.?
Heathrow has spent 36 million pounds ($57 million) on upgrading its winter weather equipment since 2010 -- a year that saw it face heavy criticism after it almost shut down when snow hit just before Christmas. It now has 130 snow-clearing vehicles.?
More than 400 flights were canceled on Friday, while on Saturday 111 flights, most of them operated by IAG's British Airways, were canceled and hundreds of passengers spent the night in Heathrow's terminals.?
Watch World News videos on NBCNews.com
BA said there had been a knock-on effect because many of its planes were in the wrong place after Friday's snow.
"Like other airlines at Heathrow we have complied with a request to reduce our schedule by 20 percent on Sunday and we continue to work with Heathrow Airport to help keep the airport running as smoothly as possible," BA said in a statement.?
"We are doing everything we can to help customers whose flights have been disrupted by severe weather."
PhotoBlog: Hundreds of flights canceled at Heathrow due to snow
Services by Air France-KLM, Ireland's Aer Lingus and Germany's Lufthansa have also been affected.?
France's SNCF railway company announced delays of up to 40 minutes on many lines as drivers were ordered to reduce speed as a safety measure.?
Local media said some 25,000 homes lost power in southwestern France.?
($1 = 0.6304 British pounds)
Additional reporting by Rosalba O'Brien in London, and Brian Love and Gerard Bon in Paris.
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Saturday, January 19, 2013
Like It Or Not, 3D Printing Will Probably Be Legislated
As the race – and it’s basically a race – to release as many 3D-printed gun parts as possible heats up, it’s never been harder for me to come down on the side of the “Freedom To Tinker” crowd. Last weekend Defense Distributed, a group dedicated to releasing plans for a 3D printed gun, posted a video and description of their 3D-printed AR-15 thirty-round magazine. The video, which is, unnecessarily, full of snarky vitriol, shows that, on some level, the 3D printed gun isn’t very far off. It also shows that the call for 3D printer legislation could soon overpower the call for freedom. The problem with childish displays of firepower coupled with “How’s that national conversation going?” is that it proves that the folks who are doing this tinkering are less than responsible. They feel that this is a freedom of speech issue rather than a gun control issue. It’s abundantly clear that the lads at Defense Distributed are enjoying their newfound notoriety and, like a boy band on their first tour, they’re ready to trash some hotel rooms. The resulting shenanigans have convinced Congressman Steve Israel (D-NY) to call for the banning of undectable 3-D printed high-capacity magazines. He updated his website yesterday, writing: Rep. Israel said, ?Background checks and gun regulations will do little good if criminals can print high-capacity magazines at home. 3-D printing is a new technology that shows great promise, but also requires new guidelines. Law enforcement officials should have the power to stop keep homemade high-capacity magazines from proliferating with a Google search.? The law would “make it illegal to manufacture, own, transport, buy, or sell any firearm or magazine that is homemade and not detectable by metal detector and/or does not present an accurate image when put through an x-ray machine.” It is a noble if quixotic goal. Politics, as we’ve learned, is woefully unprepared to handle major technological advancement. While Israel means well, his ability to keep an 3D model off of Google is laughable at best and dangerous at worst. As a gun control proponent, I know that now, more than ever, we need sane and effective controls on weapons in our country. As a believer in the unfettered growth of technology, on the other hand, I will defend Defense Distributed to the death while hating their crass methodology. Israel’s efforts only serve to give the DD kids a frissonSource: http://feedproxy.google.com/~r/Techcrunch/~3/Lk0Bd1RAgd0/
Contract Technical Writer with S1000D bgr, large avionics doc set ...
Job Code: CAJ-327
Cash/Prizes: 1099 or corp-to-corp (or W2 by request)
Audience: Jet engine maintenance/repair mechanics
Location: Entirely onsite in Hartford, CT
Starts: Late March/early April, 2013
Duration: Full-time, 40 hrs/week, nine (9) months, renewable
Relocation/Visa assistance: No
Representation: Principals only, please
Our respected aviation industry client needs a contract Technical Writer with solid S1000D documentation experience to update maintenance and repair manuals for jet engines.
Initially you?ll support a massive data conversion initiative (from SGML to S1000D v4.01) by implementing edits and updates, and cleaning up converted content. Once the conversion phase completes, you?ll transition into an open-ended contract role authoring S1000D documentation.
If you?ve authored multiple S1000D deliverables, know how to create and revise data modules, and are comfortable using Simplified English, you?re a strong candidate.
This will be full-time (40 hours/week), fully onsite work in Hartford, CT, beginning in late March or early April and extending through (at least) the end of 2013. You?d be paid on a 1099 basis, unless you prefer W2.
Required:
- Strong experience implementing the S1000D documentation standard
- Working knowledge of Simplified English
- Sharable, relevant writing samples and reachable references
- Full-time, long-term availability
- Ability to work onsite in Hartford, CT (traveling at your own expense)
Desired:
- Experience working in the avionics industry documenting the maintenance of commercial jet engines and/or airframes
- Exposure to S1000D products from Corena
To apply:
Please visit contentrules.com/apply, citing ?CAJ-327? in the Job Code field.
Note: Content Rules has many content-development opportunities with SF Bay Area technology companies. Visit www.contentrules.com/jobs for details.
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?Thursday, January 17, 2013
Peter Robinson : Keep Your Guns. Move to Texas
As if we needed any more reasons to thank God for Texas, this very day has produced two new ones:
By the governor of Texas, Rick Perry, a statement:
The piling on by the political left, and their cohorts in the media, to use the massacre of little children to advance a pre-existing political agenda that would not have saved those children, disgusts me, personally. The second amendment to the Constitution is a basic right of free people and cannot be nor will it be abridged by the executive power of this or any other president.
By the attorney general of Texas, Greg Abbott, an invitation:
Keep your guns. ?Come to Texas.
Here in Texas, you will have the liberty and the opportunity to achieve your dreams. On top of that, we have no income tax, yet still manage to have a multi-billion dollar budget surplus.
We have right to work laws and a reasonable regulatory environment. Texas has created more than 275,000 jobs in the last year alone! And we?ll fight like hell to protect your rights.
You?ll also get to keep more of what you earn and use some of that extra money to buy more ammo.
On a day when Republicans in 49 states are sounding overwhelmingly apologetic and defensive, thank God for the two leading Republicans in the fiftieth.
Source: http://www.ricochet.net/main-feed/Keep-Your-Guns.-Move-to-Texas
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Tuesday, January 15, 2013
Coach Kelly's Walter Camp Award Speech...
WELCOME TO THE NOTRE DAME FAMILY!
Jim Small's ND GO IRISH BLOG was created for alumni, parents, fans and friends everywhere -- of the University of Notre Dame. This site will share positive stories "every day" about Notre Dame and its; students, alums, faculty, staff, administration, teams, coaches, groups, musicians, etc. -- and, anything else we can find that's newsworthy, entertaining or heartwarming concerning "Our Lady's University."The University of Notre Dame has asked that I let you know this blog is not affiliated, sponsored or endorsed by them...
Besides being a lifelong fan of the University of Notre Dame, my wife Susan and I are the proud parents of three great kids; Jimmy (a former Irish Guard), Kara and Brady. I also "triple" as a Senior Director of Marketing & Communications at Notre Dame. So, if you ever have a story idea, thoughts on how this blog can better serve Notre Dame fans, or you just want to talk Notre Dame -- feel free to reach me at; jim.small@ndgoirish.com
GO IRISH!
SONGS OF THE FIGHTING IRISH!
Source: http://notredamegoirish.blogspot.com/2013/01/coach-kellys-walter-camp-dinner-speech.html
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Expect traffic changes at Santa Ana College Jan. 14
SANTA ANA - Santa Ana College officials said that people heading to campus can expect some traffic changes beginning Monday, Jan. 14, as the result of ongoing construction on campus that is expected to be completed this spring.
The College Avenue entrance at 17th Street will open Jan. 14.
The Bristol Street campus entrance will be closed to allow for its reconfiguration.
Students and staff will be asked to use alternate entrances: Pacific Avenue via Washington Avenue, College Avenue via 17th Street, or the main entrance on 17th Street.
The campus improvements are funded by Measure E, a $337 million general obligation bond, passed by voters in 2002.
Source: http://www.ocregister.com/news/street-383270-avenue-college.html
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Saturday, January 12, 2013
St. Andrew's In Tangier: A Church With Muslim Art
Being in Morocco, Tangier is a mostly Muslim city. Being a port, it's also a mixed city with a long history of Christian and Jewish influence. That interesting blend comes out in the language, music, art and cooking. You can see Tangier's mix of cultures everywhere.
Even in the churches.
The Church of St. Andrew is an Anglican congregation close to the Place du Grand Socco. The first thing you'll notice is the church tower shaped like the square, Moorish-style minarets so common in the mosques here. The only difference is the English flag flying from the top and the lack of a loudspeaker to broadcast the Muslim call to prayer.
Entering the churchyard, you'll find a shady oasis of trees, shrubs and a well-manicured garden. Cats lounge amid the headstones, which include several for the fallen from various Allied armies during World War II. This part of the property looks like a regular English churchyard except for the palm trees and lack of moss on the headstones. Go inside, however, and you'll see something quite different.
The interior has several Islamic touches. The doors have rounded arches and elaborate carvings. The carved and painted wood ceiling looks like something from a Moorish palace. The arch just before the altar is the most elaborate and looks like it came from a Muslim palace. Arabic calligraphy spells out the words "bismi-ll?hi r-ra?m?ni r-ra??m" (In the name of God, the most Gracious, the most Merciful), which is the first line of each Surah (chapter) of the Koran.
Gallery: St. Andrews Church, Tangier
So how did a verse from the Koran end up decorating an Anglican church in a Muslim country? The story starts in 1880, when the Sultan, Hassan I, gave land to the British expat community in Tangier so they could build a church. One was built but soon proved too small for the growing Christian community and so the present church was built in 1894. It was consecrated in 1905.The design includes Islamic styles as a way of recognizing the friendly relations between the UK and Morocco and to honor the memory of the Sultan's donation. The work was done by Moroccan craftsmen.
St. Andrew's is by no means unique. During the height of Islamic civilization during the Middle Ages, European art and architecture borrowed frequently from Muslim styles. European artists copied Islamic styles and even included Arabic calligraphy in Christian works of art. Check out the gallery for a couple of surprising examples.
Don't miss our other posts on Tangier! Coming up next: The Anatomy Of A Perfect Hotel!
[Photo by Sean McLachlan]
Filed under: Arts and Culture, History, Learning, Africa, Morocco, Middle East
Source: http://www.gadling.com/2013/01/11/st-andrews-in-tangier-a-church-with-muslim-art/
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New breast cancer technology comes to Yakima | Local & Regional ...
YAKIMA, Wash. -- New breast cancer screening technology made its way to Yakima. The Ohana Mammography Center recently installed the new digital equipment.
The upgrade cost more than a million dollars for two machines.
They give doctors clearer images than ever and it's faster than a traditional mammogram.
Doctors also don't have to wait for the film to develop.
"It's a lot quicker -- the images come up in about 30 seconds after we take them and it's interactive, so when we have the patient in here she can look at them at the same time," said Nancy Roehr of the Ohana Mammography Center.
The new machines also gives off about a third less radiation.
Ohana is part of Yakima Valley Memorial Hospital.
Source: http://www.kimatv.com/news/local/New-breast-cancer-technology-makes-mammograms-faster-186366841.html
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Fluid from Pap test used to detect ovarian, endometrial cancers ...
(Reuters) ? Using cervical fluid collected from routine Pap smears, U.S. researchers were able to spot genetic changes caused by both ovarian and endometrial cancers, offering promise for a new kind of screening test for these deadly cancers.
Experts say that although the test has tremendous potential, it is still years from widespread use. But if proven effective with more testing, it would fill a significant void.
Currently, there are no tests that can reliably detect either ovarian or endometrial cancer, which affects the uterine lining. Research teams have been trying for several years to find a screening test that could identify these cancers early, when there is a better chance of a cure.
?Pap smears have had a tremendous impact in reducing the rate of cervical cancer in the United States,? said Dr. Andrea Myers of Dana-Farber Cancer Institute, a co-author of the commentary on the study published in Science Translational Medicine.
?The lack of an equally effective screening test for women at high risk for endometrial or ovarian cancer has created a great deal of interest in developing tests that could identify these cancers by their genetic ?signature? ? the collection of specific mutations within them,? she said.
?This new study is an important step in that direction.?
The new approach, developed by a team at Johns Hopkins Kimmel Cancer Center in Baltimore, piggybacks on routine Papanicolaou or Pap testing, which is already done routinely to detect cervical cancer.
The idea is to take fluid collected from the cervix for Pap tests and use gene sequencing technology to look for genetic changes that would only be found in endometrial and ovarian tumors.
Since Pap tests occasionally contain cells shed from the ovaries or the lining of the uterus, cancer cells from these organs could be present in the fluid as well.
The team tested for mutations in 24 endometrial and 22 ovarian cancers.
?EXCITING FIRST STEP?
?We could detect 100 percent of endometrial cancers and 40 percent of ovarian cancers, even at the earliest stages of their disease, and we can do it without any false positives,? said Dr. Luis Diaz, associate professor of oncology at Johns Hopkins, who worked on the study published on Wednesday in Science Translational Medicine.
Diaz called the study ?an exciting first step.?
?We?re seeing high sensitivity in endometrial cancer. We?re seeing moderate sensitivity in ovarian cancer, and we?re seeing no false positives,? he said.
That offered enough rationale to start tests on 100 ovarian cancers of different stages and 100 endometrial cancers, as well as a large number of samples from healthy women.
The team hopes to complete that testing by the end of the year.
Dr. Shannon Westin, an expert in gynecologic cancers at the University of Texas MD Anderson Cancer Center, said the need for a screening test for these two cancers is great.
In the United States, the two cancers combined are diagnosed in 70,000 women each year, and about 23,500 women will die from these cancers.
Westin, who co-wrote a commentary on the study, said the paper is ?very compelling and very interesting? that you could find evidence of these cancers in a screening test using fluid from Pap tests.
But the test must still be validated and shown to be effective in a large populations of women, a process that could take 10 to 15 years.
?It?s a great first step. It is a proof of principle that this can be done. Patients are used to getting the Pap smear. They understand it,? she said. That might mean women would ultimately be comfortable getting this type of test.
Dr. David Chelmow, a professor of obstetrics and gynecology at Virginia Commonwealth University Medical Center, who was not involved with the research, said it would be ?fantastic? to have a test that would reliably detect cancers.
?It?s an innovative idea. It?s neat. But the question is really going to be what happens when this gets more thoroughly tested,? he said.
Diaz said currently there are no tests to screen for these cancers early. The experimental test would cost about $100, but with the falling cost of sequencing technology, he estimates it will be half or even a tenth of that cost within the next year.
Full article can be found here.
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Thursday, January 10, 2013
Hands-on with Gigabyte's S1082 and S1185 Windows 8 tablets
Gigabyte came to CES with a pair of Windows 8 tablets, the S1082 and S1185, in hopes of making a splash in a US market that still tends to associate the company name with PC motherboards. We had the opportunity to try both, and came away intrigued -- there's a handful of touches on each that separate them from the pack. Read after the break for our impressions, and check back for video soon.
Continue reading Hands-on with Gigabyte's S1082 and S1185 Windows 8 tablets
Filed under: Tablets
Source: Gigabyte (1), (2)
Source: http://www.engadget.com/2013/01/09/hands-on-with-gigabytes-s1082-and-s1185-windows-8-tablets/
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Tuesday, January 8, 2013
Flame retardant pollutants found at far-flung locations, including Indonesia, Nepal and Tasmania
Jan. 8, 2013 ? Chemicals used as flame retardants are present as environmental pollutants at locations around the globe, including remote sites in Indonesia, Nepal and Tasmania, according to a study by researchers from the Indiana University School of Public and Environmental Affairs.
The study, published this month in the journal Environmental Science and Technology, makes use of a novel but highly effective sampling technique: measuring concentrations of the chemicals in the bark of trees, which absorbs compounds in both vapor and particle phases.
"These findings illustrate further that flame retardants are ubiquitous pollutants and are found all around the world, not only in biota and humans but also in plants," said Amina Salamova, a research associate in the School of Public and Environmental Affairs at IU Bloomington and co-author of the study with Ronald A. Hites, Distinguished Professor in SPEA and in the Department of Chemistry in the College of Arts and Sciences.
The study measured concentrations of brominated and chlorinated flame retardants collected in tree bark samples at 12 locations around the globe: three sites in Canada and single sites in Iceland, Ireland, Norway, Czech Republic, South Africa, Nepal, Indonesia, Tasmania and American Samoa.
The highest concentrations were found at an urban site: Downsview, Ontario, Canada, near Toronto. However, the second-highest concentration of one type of flame retardant, Dechlorane Plus, was found at a remote site at Bukit Kototabang in Indonesia. Researchers don't know the cause of the relatively high concentrations at the site but suspect it may be near a source.
The study was carried out in cooperation with the Global Atmospheric Passive Sampling network, an international monitoring initiative established in 2004 on six continents.
Brominated and chlorinated flame retardants have been used for several decades in consumer products made of plastic, foam, wood and textiles to prevent combustion and slow the spread of fire. They persist in the environment and bio-accumulate in ecosystems and in human tissues. Exposure to the compounds has been associated with thyroid and other endocrine system disruption and with adverse neurological development. As a result, the production and use of certain flame retardants has been restricted in North America and the European Union.
Researchers measured a variety of flame retardants, including widely used polybrominated diphenyl ethers, or PBDE, as well as nonregulated compounds such as Dechlorane Plus and "older" flame retardants that were used in the 1980s. Findings included:
- Most of the compounds were detected at all the locations, with concentrations varying widely.
- Concentrations were associated with population density, suggesting the compounds most likely entered the environment through their use in nearby homes and offices.
- Concentrations found in tree bark are correlated with those measured in previous atmospheric sampling at the sites by the Global Atmospheric Passive Sampling network.
Higher concentrations of flame retardants in bark and the atmosphere have been found by Hites and others in previous studies of the Great Lakes region, especially urban areas near Chicago and Cleveland, and also at cities in China. Even higher concentrations were found in southern Arkansas and at Niagara Falls, N.Y., near the sites of manufacturing facilities for PBDE and Dechlorane Plus, respectively.
The study also confirms the effectiveness of using tree bark as a sampling medium, a technique that Hites and colleagues have used in previous studies of persistent organic pollutants such as flame retardants.
Bark makes an effective sampling medium because of its large surface area and high lipid content. The samples are easy and inexpensive to collect, an advantage in developing countries that lack funding for extensive environmental monitoring programs. Tree bark also collects both vapor and particle phase pollutants, while other samplers collect one or the other.
Support for the study came from the Great Lakes National Program Office of the U.S. Environmental Protection Agency.
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The above story is reprinted from materials provided by Indiana University, via Newswise.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Amina Salamova, Ronald A. Hites. Brominated and Chlorinated Flame Retardants in Tree Bark from Around the Globe. Environmental Science & Technology, 2013; 47 (1): 349 DOI: 10.1021/es303393z
Note: If no author is given, the source is cited instead.
Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.
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Ovarian cancer stem cell study puts targeted therapies within reach
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Public release date: 7-Jan-2013[ | E-mail |
Share ] Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer therapies, is published online in the current issue of Cell Cycle.
Lead author Yingqun Huang, M.D., associate professor in the Department of Obstetrics, Gynecology & Reproductive Sciences, and her colleagues have demonstrated a connection between two concepts that are revolutionizing the way cancer is treated.
First, the "cancer stem cell" idea suggests that at the heart of every tumor there is a small subset of difficult-to-identify tumor cells that fuel the growth of the bulk of the tumor. This concept predicts that ordinary therapies typically kill the bulk of tumor cells while leaving a rich environment for continued growth of the stem cell tumor population.
The second concept, dubbed "seed and soil," defines a critical role for the tumor cells' "microenvironment," which is the special environment required for cancer cell growth and spread.
"Both concepts have particular relevance for the treatment of adult solid tumors such as ovarian cancer, which has been notoriously difficult to diagnose and treat," said co-author Nita J. Maihle, professor in the Department of Obstetrics, Gynecology & Reproductive Sciences and a member of Yale Cancer Center. "Ovarian cancer patients are plagued by recurrences of tumor cells that are resistant to chemotherapy, ultimately leading to uncontrolled cancer growth and death."
In this study, Huang and her colleagues were able to define a molecular basis for the interplay between these two concepts in ovarian cancer. They did this by using sophisticated gene sequencing methods to demonstrate a regulatory link between the stem cell factor Lin28 and the signaling molecule bone morphogenic protein 4 (BMP4).
"These results are supported by the latest molecular ovarian cancer prognosis data, which also suggest an active role for the tumor microenvironment in ovarian carcinogenesis," said Huang and Maihle. "Together these studies reveal new targets for the development of cancer therapies."
###
Other authors on the study include Wei Ma, Jing Ma, Jie Xu, Chong Qiao, Adam Branscum, Andres Cardenas, Andre T. Baron, Peter Schwartz, and Nita J. Maihle.
The study was funded by a 09SCAYALE14 Connecticut Stem Cell Grant and a 1063338 Albert McKern Scholar Award to Huang, and a Yale School of Medicine "Senior Women in Medicine" Professorship to Nita J. Maihle.
Citation: Cell Cycle Vol. 12, Issue 1
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 7-Jan-2013[ | E-mail |
Share ] Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University
Researchers at Yale School of Medicine have identified a key link between stem cell factors that fuel ovarian cancer's growth and patient prognosis. The study, which paves the way for developing novel targeted ovarian cancer therapies, is published online in the current issue of Cell Cycle.
Lead author Yingqun Huang, M.D., associate professor in the Department of Obstetrics, Gynecology & Reproductive Sciences, and her colleagues have demonstrated a connection between two concepts that are revolutionizing the way cancer is treated.
First, the "cancer stem cell" idea suggests that at the heart of every tumor there is a small subset of difficult-to-identify tumor cells that fuel the growth of the bulk of the tumor. This concept predicts that ordinary therapies typically kill the bulk of tumor cells while leaving a rich environment for continued growth of the stem cell tumor population.
The second concept, dubbed "seed and soil," defines a critical role for the tumor cells' "microenvironment," which is the special environment required for cancer cell growth and spread.
"Both concepts have particular relevance for the treatment of adult solid tumors such as ovarian cancer, which has been notoriously difficult to diagnose and treat," said co-author Nita J. Maihle, professor in the Department of Obstetrics, Gynecology & Reproductive Sciences and a member of Yale Cancer Center. "Ovarian cancer patients are plagued by recurrences of tumor cells that are resistant to chemotherapy, ultimately leading to uncontrolled cancer growth and death."
In this study, Huang and her colleagues were able to define a molecular basis for the interplay between these two concepts in ovarian cancer. They did this by using sophisticated gene sequencing methods to demonstrate a regulatory link between the stem cell factor Lin28 and the signaling molecule bone morphogenic protein 4 (BMP4).
"These results are supported by the latest molecular ovarian cancer prognosis data, which also suggest an active role for the tumor microenvironment in ovarian carcinogenesis," said Huang and Maihle. "Together these studies reveal new targets for the development of cancer therapies."
###
Other authors on the study include Wei Ma, Jing Ma, Jie Xu, Chong Qiao, Adam Branscum, Andres Cardenas, Andre T. Baron, Peter Schwartz, and Nita J. Maihle.
The study was funded by a 09SCAYALE14 Connecticut Stem Cell Grant and a 1063338 Albert McKern Scholar Award to Huang, and a Yale School of Medicine "Senior Women in Medicine" Professorship to Nita J. Maihle.
Citation: Cell Cycle Vol. 12, Issue 1
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-01/yu-ocs010413.php
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